Maryland Sports Betting » Predictions & Expert Picks » NFL Picks » San Francisco 49ers VS Washington Commanders NFL Week 16 Predictions with odds, betting lines, picks and promos

San Francisco 49ers VS Washington Commanders NFL Week 16 Predictions with odds, betting lines, picks and promos

The Washington Commanders (7-6-1) take to the road to face the San Francisco 49ers (10-4) at the Levi’s Stadium on Saturday for a Week 16 matchup. The San Francisco 49ers have already clinched the NFC West title with ten wins in 14 games going into this match, while the Washington Commanders sit fourth in the NFC East with seven victories. The San Francisco 49ers are the big favorites to snatch the win on the moneyline. Considering how strongly the oddsmakers rate their chances against the Washington Commanders, the home crowd will be anything but impressed if they somehow slip up.

CompanyBonusConsVisit
FanDuel Sportsbook Bet $5, get $150 in bonus bets Bet now FanDuel Maryland review

San Francisco 49ers VS Washington Commanders Betting lines

San Francisco 49ers VS Washington Commanders Betting expert picks

San Francisco 49ers VS Washington Commanders Moneyline

Picking the San Francisco 49ers is a no-brainer in our eyes. The oddsmakers rate their chances of success on Saturday at 77%, and given their decent run of form at home, it’s easy to see why. The 10-4 hosts have won four of their last five matches at the Levi’s Stadium, leaving their home record for the season at 6-1. On the other hand, a Washington Commanders win is priced at +265, with the visitors 4-2 on the road and 7-6 overall for this season.

San Francisco 49ers VS Washington Commanders Spread

The San Francisco 49ers are the 7 point favorites over the Washington Commanders in the Week 16 betting lines. This leaves the hosts favored to take the win by more than a touchdown on Saturday. The nine most recent matchups in this series have seen an average points margin of 10.1 points.

Having covered the spread in their last three home matches, the San Francisco 49ers look like a sound choice to pull it off again at the Levi’s Stadium. In their past 12 matchups against teams from the NFC East, the San Francisco 49ers have gone 8-4 ATS and are 7-3 ATS from their past 10 matches.

The Washington Commanders, meanwhile, have covered the spread in four of their last five games on the road. In their past 10 matches, the Washington Commanders went 6-3-1 ATS and also ended up 4-5 ATS from their nine most recent road trips.

San Francisco 49ers VS Washington Commanders Total

There was an average of 39.11 points scored in the previous nine clashes between the San Francisco 49ers and the Washington Commanders.

The two squads played four of these nine encounters at the Levi’s Stadium, producing a combined 40.25 points on average to go over the total two times. For this latest matchup on Saturday, the total is currently set at 38.0 points.

The total has averaged 43.1 points in the San Francisco 49ers’ ten most recent games, as well as 42.0 points in their last five at home. Meanwhile, betting on the over would’ve paid out as a winning bet in the last three games at Levi’s Stadium for the San Francisco 49ers, who are 6-4 in their last ten home and away matches combined.

In the last four matches the Washington Commanders played, the total went under. Going on the road doesn’t always seem to produce the expected number of points for the Washington Commanders, as the total has gone under in seven of the past 12 matchups away from home.

CompanyBonusConsVisit
BetMGM Sportsbook Up to $1,000 First Bet Insurance
  • JOKERZINO
  • Get your stake back if you miss a leg
  • Parlay+: 40% more in winning profits
Bet now BetMGM Maryland review

San Francisco 49ers VS Washington Commanders Betting trends

  • San Francisco 49ers have covered the spread in their last five games.
  • Washington Commanders have covered the spread in four of their last five games away
  • six of Washington Commanders’ last seven away games went under
CompanyBonusConsVisit
Caesars Sportsbook Up to $1,500 in bet credits
  • JOKERZBETPICS
  • Get a $100 bonus, win or lose
  • Or, get up to $1,500 in credits
Bet now Caesars Sportsbook MD

NFL Power Rankings Week 16 2022, San Francisco 49ers VS Washington Commanders

San Francisco 49ers Form

The San Francisco 49ers are on a great run of form after making it seven wins in a row by beating the Seattle Seahawks 13-21 last week, leaving them 8-2 in their last 10 matches.

The San Francisco 49ers rank tenth in the NFL’s offensive rankings, averaging 24.1 points this season and 25.3 points at the Levi’s Stadium. Defensively, the hosts have the best unit of all 32 teams, allowing just 15.0 points on average and 14.3 points on their own field.

The San Francisco 49ers have clinched a playoff berth after winning their division. The NFC West champions now aim to improve their third seed in the NFC Conference going into the final weeks of the regular season.

Washington Commanders Form

The Washington Commanders fell to a 12-20 defeat to the New York Giants in their most recent outing, leaving them 6-3-1 from their last ten matches.

The Washington Commanders bring an offense that has struggled to click into gear this season, putting up just 18.9 points per game. The visiting defense, however, looks more than capable of taking on any offense at any place, having allowed just 19.3 points on the road this year to post the ninth-best away record.

The Washington Commanders began the regular season backed to make the playoffs, and having gone 7-6 from 14 games so far, they’re on course to reach this target. The aim now for the away team is to at least maintain or improve on its seventh seed in the NFC Conference.

CompanyBonusConsVisit

San Francisco 49ers VS Washington Commanders H2H history

The Washington Commanders bagged a 15-23 win over the San Francisco 49ers in the previous matchup between these two franchises. The encounter took place in December 2020. The San Francisco 49ers have enjoyed the upper hand over the Washington Commanders from their previous nine matchups. The home side collected five wins to go 5-4 in this series and will look to continue its dominance at Levi’s Stadium.

In their last nine head-to-head games, the San Francisco 49ers managed 19 points on average per game, while the Washington Commanders put 20.11 points on board.

San Francisco 49ers VS Washington Commanders Standings